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Bioxet Body Hair Inhibitor And Skin Care Créme

Anadolu university, faculty of pharmacy,department pharmaceutical technologies cosmetology department 26470 eskiserhir, Bioxet body hair inhibitor and skin care crème.


BIOXET BODY HAIR INHIBITOR AND SKIN CARE CRÈME

In the study performed on volunteers of ages between 39 ±9consisting of 20 subjects (13 females and 7 males) for a period of 3 months the following results were obtained:

• BIOXET crème demonstrated 3% increase in the moisture level of the skin. When BIOXET crème applied, the areas were compared with other areas statistically, and a significant difference was observed.

• Percentage increase in the skin sebum of the area applied with BIOXET crème was found to be four times higher in comparison to the other areas.
• pH value of skin applied with BIOXET crème was determined as 5.22. Other areas were more acidic and a statistical difference was observed between the areas.
• As a result of the melanin and erythema measurements it was determined that BIOXET crème is safe for dermatological use.
• It was observed that BIOXET crème ensures a significant amount of decrease in the number and diameter of body hair.

As a result it was determined that BIOXET crème is safe for dermatological purposes and is a physico-chemically stable product ensuring a significant decrease in the number and diameter of body hair and having positive effects on skin moisture and sebum when applied for a period of 3 months.

Anadolu university, faculty of pharmacy, department pharmaceutical technologies cosmetology department 26470 eskiserhir, Physical tests.


Physical tests

On the freshly prepared BIOXET crème microbiological and rheological analyses were performed; its pH value was measured and crème was physically examined.

Results:

• BIOXET crème is seen as a homogenous crème and no phase separation was observed.
• It is off-yellow resulting from herbal extract.
• Viscosity of BIOXET crème was 2825 mPas sec and it is suitable for applications to the skin.
• Dew dimensions of BIOXET crème is 2.698 µm and is suitable for applications to the skin.
• No microorganisms that would cause problems in respect for applications of the crème were observed in the microbiological analyses.

 

Stability tests storing conditions

BIOXET crème samples were stored under conditions; 60% relative humidity and 4oC, 25oC, 40oC and -40oC for a period of 3 months.

• No changes in appearance or phase separation were observed.
• Off yellow color of the BIOXET crème became darker in every medium in speeded up stability conditions (fridge, room temperature, strove, acclimatization cabin). This situation indicates that crème should be filled in oxygen-free mediums and be kept in tightly sealed, colored vessels with small application holes.
• No change in pH value was observed.
• Viscosity changes were observed during storage of BIOXET crème. Yet the interval of change was not extensive enough to provide problems for application.
• Dew dimensions of BIOXET crème is between 1-10 µm, which is required for a cosmetics preparation.
• No microorganism that might cause problems in respect for applications were observed in microbiological analyses.

 

Efficacy tests BIOXET crème

Body hair inhibitor BIOXET crème had positive effects on moisture of the skin (19.24%-36.23%) and on sebum (37.94%-1577.0%) and it did not cause any dramatic changes in the pH of skin ((-1.5) %- (-22.1) %).

1.41% increase in the forearm erythema value is in the acceptable limits. That is the use of product is safe.

A significant decrease was obtained in the length of body hair (8.68%-28.10%) and diameter of body hair (17.68%-26.60%) for body hair in legs and arms.